Barcelona are without the services of seven first-team players for Sunday's La Liga clash with Real Betis.
Marc-Andre ter Stegen, Gavi, Marcos Alonso, Inigo Martinez, Joao Cancelo and Raphinha are all unavailable for selection in Seville due to injury problems.
Meanwhile, Andreas Christensen is also absent due to the muscular problem which he picked up in the team's 3-1 success over Unionistas in the Copa del Rey on Thursday.
The squad has received a double boost from the cup fixture, though, with Ronald Araujo and Lamine Yamal available again after missing out against Unionistas through suspension.
Hector Fort and Pau Cubarsi could both be in line for minutes due to the defensive absentees, although it seems more likely that Sergi Roberto will line up on the right of the back four.
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Barcelona have not been in La Liga action since recording a 2-1 win over Las Palmas on January 4, and they are currently fourth in the table, eight points behind the leaders Girona.
"Tomorrow we have a tough match. They haven't lost at home. We're starting the second half of the season with all our enthusiasm, knowing that we're behind Girona and Madrid, but we'll be able to come back from behind," Barcelona boss Xavi told reporters during his pre-match press conference.
"It's the best scenario to see a good Barca and win, based on good play... defensively we are very good, we are also very good at pressing high. We win balls back and we are excellent in strategy.
"I'm talking about the last pass, to choose well, but we have very young players. I despair because I see the pass, which was my quality, but it's a matter of time. It was not a criticism. It's a feeling of desperation from me. The youngsters have to keep trying."
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Xavi also remains confident that his side can win three trophies this season, with the Catalan team aiming for success in La Liga, the Champions League and the Copa del Rey.
"We're optimistic that we can make up the six or seven points that we're behind. We are starting the second half of the season with maximum enthusiasm," he added.
"Yes, I firmly believe that (team can win three trophies). You can't be sure of winning. There are many clubs that haven't won for many years. We have done it with the majority of last year's squad."
Xavi also revealed that Cancelo was close to being involved against Real Betis, with the Portuguese potentially making his return in the quarter-finals of the Copa del Rey against Athletic Bilbao next week.
Barcelona squad vs. Real Betis:
Pena, Astralaga, Kochen; Balde, Araujo, Kounde, Cubarsi, Fort; Pedri, Romeu, Roberto, De Jong, Gundogan, F Lopez; F Torres, Lewandowski, Felix, Roque, Yamal, Guiu
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